Topics include: Modeling Human Cancer in Mice, CRISPR/Cas for Mouse Model Creation and more
Emory Clinic C Conference Room 5012 Kauffman Auditorium
Thursday, September 17, 2015
10:00 am - 2:00 pm |
Whether you are new to using mouse models of disease or a seasoned professional, The Jackson Laboratory has valuable tools and resources to assist you. Come join us to learn helpful tips and receive training that will give you the tools you need for your research. See below for more details about seminar topics.
* Lunch will be provided to registered participants |
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Modeling Human Cancer in Mice
10:00 - 11:00 am
In this seminar, you will learn:
- Immune deficient hosts for tumor xenograft modeling
- Patient–derived xenograft (PDX) models and their advantages for in vivo preclinical compound
evaluation
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Modeling Human Malignancy with Patient-Derived Xenograft Cancer Models
11:00 am - 12:00 pm
In this seminar, you will learn:
- Learn how more than 280 PDX models have been established in partnership with a consortium of
cancer hospitals and clinical trial teams
- Appreciate how the diversity of the PDX program represents current patient demographics
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Lunch will be provided to registered participants
12:00 - 12:30 pm |
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Beyond the Knockout: Using Cre-lox Technology to Model Cancer, Neurodegenerative
Diseases and More
12:30 - 1:30 pm
In this seminar, you will learn:
- How Cre-lox technology is being used to model various human cancers, including early malignancy
in lung adenocarcinoma, breast cancer and melanoma
- How Cre-lox technology is furthering our understanding of Amyotrophic Lateral Sclerosis (ALS),
Parkinson’s Disease and other neurodegenerative disorders
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CRISPR/Cas for Mouse Model Creation
1:30 - 2:00 pm
In this seminar, you will learn:
- Creation of both knock-out and knock-in mouse models and the efficiency
- Success with various strain backgrounds and unsurpassed health status of founder mice
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