The Jackson Laboratory

JAX Seminars
Scientific Education for your Institution

Scientific experts from The Jackson Laboratory will be hosting an online seminar for your institution to provide comprehensive training and tools necessary for your research.

Discussion Topics:
Caring for Immunodeficient Mice and Predictive Cancer Models using Patient-Derived Xenograft Mice



Event Details:
CONGENTO
Online WebEx Event
Thursday, October 1, 2020
2:00 PM - 4:00 PM Western European Summer Time


Presented by:
Grace Berryhill, Ph.D.
Technical Information Scientist
The Jackson Laboratory

Agenda

Caring for Immuno-Deficient Mice from Nude to NSG™

2:00 PM - 3:00 PM Western European Summer Time

The revolutionary NOD scid gamma (NSG) mouse model is used by investigators worldwide as a “humanized” preclinical model and as a host for human patient-derived cancer xenografts. Whether you currently use NSG mice or plan to, join us to learn more about the practical aspects of maintaining these mice, including:

  • Immunodeficiency in mouse colonies
  • An overview of the characteristics and uses of NSG mice in research
  • Types and signs of common infections
  • Recommended housing conditions and husbandry processes for successful care of immunodeficient mice

Predictive Cancer Models Using Patient-Derived Xenograft Mice

3:00 PM - 4:00 PM Western European Summer Time

Do you need pre-clinical models that represent the diversity of cancer patient demographics? Using patient-derived xenograft (PDX) mice enables modeling the heterogeneity of human cancer and conducting more translationally-relevant cancer research studies. Join this seminar to learn about:

  • A collection of 450 PDX models that have been established in partnership with a consortium of cancer hospitals and clinical trial teams
  • How the genetics, pathology, and treatment response of PDX tumors reflect clinical observations
  • Using tumor-bearing humanized NSG mice as an innovative platform to evaluate immunotherapies
  • Finding relevant cancer models and characterization data using the “Mouse Tumor Biology Database”